Translating interventional device innovations from the lab to the patient bedside: applications within the head

Date: 2022/06/10 - 2022/06/10

Academic Seminar: Translating interventional device innovations from the lab to the patient bedside: applications within the head

Speaker: Yang Liu, Assistant Professor, UM-SJTU Joint Institute, Shanghai Jiao Tong University

Time: 10:00 - 11:30, June 10, 2022 (Beijing Time)



We are living in this aging society with an unprecedented size of population suffering from neurological disorders. Among all, stroke is one of the most prevalent and lethal disorders. Stoke is the No. 1 cause of death in China. Over 80% of all stroke cases are caused by blood clots occluding the vessels supplying blood to the brain. For large vessel occlusion which accounts for about 1/3 of all stoke cases, interventions with thrombectomy devices to mechanically remove clots have become the standard of care since 2015. Although thrombectomy devices have evolved for about 20 years, clinical challenges persist. Complete clot removal is achieved in about 50% of the cases and only 35% of patients can completely restore the blood flow after the first interventional attempt. In this talk, I will demonstrate the mechanism and device technology for an innovative thrombectomy device and how a close collaboration between engineers and clinicians can translate device innovations from the lab to the patient bedside. At the end of this talk, I will also share a new interventional platform we proposed to address other commonly seen neurological disorders such as head injury, hydrocephalus, and its application in brain-computer interface.


Yang Liu is a tenure-track assistant professor at JI. Before joining JI in 2022, he was a research fellow and assistant professor in Interventional Neuroradiology at Mayo Clinic-Rochester. He received his Ph.D. degree in Mechanical Engineering from the University of Michigan in 2019 and his B.S. degree (with a minor in Finance) in Mechanical Engineering from JI in 2014. He received the Tech Transfer Talent Network Postdoc Fellowship at the University of Michigan, Pryor-Hale Award for Best Business at the Michigan Business Challenge, and Best Paper Finalist in the ASME Manufacturing Science and Engineering Conference. He has published over 40 journal papers and is a co-inventor of three international patents, of which two have been granted and licensed to the industry. He is a Scientific Advisor for Endovascular Engineering Inc, a company developing interventional devices for vascular diseases. His research is motivated by tackling unmet clinical needs.